3-Hydroxycyclopentadecene → 2-Cyclopentadecenone

HRID 2398710

반응식

HRID 2398710 반응식
[OH:1][CH:2]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH:4]=[CH:3]1>CCCCCCC.[O-2].[O-2].[Mn+4]>[CH:4]1[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:2](=[O:1])[CH:3]=1

참가 물질

4

반응물 1

HCID 544205383-Hydroxycyclopentadecene

생성물 1

HCID 540403452-Cyclopentadecenone

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 8900Heptane용매

실험 절차

3-Hydroxycyclopentadecene (20.1 g) in dried n-heptane was stirred at room temperature and a total of 100 g manganese dioxide was added in four batches of 50, 25, 15 and 10 g respectively over a period of 6 hours. After 22 hours the conversion as indicated by GLC was 100%. The mixture was filtered and the filtrate was then stirred with active charcoal and refiltered. The solvent was then removed from the filtrate under reduced pressure to yield the required product.

후처리

  1. filtrationThe mixture was filtered
  2. customThe solvent was then removed from the filtrate under reduced pressure

출처 및 근거

ORD 기록
ord-7aa3841707cb44ddaca7952cabb47e92
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04025562

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