Ammonia → 3-(3-Nitro-4-aminobenzoyl)pyridine

HRID 2399035노트

반응식

HRID 2399035 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1Cl)[C:7]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)=[O:8])([O-:3])=[O:2].[NH3:19]>C(O)C>[N+:1]([C:4]1[CH:5]=[C:6]([CH:15]=[CH:16][C:17]=1[NH2:19])[C:7]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)=[O:8])([O-:3])=[O:2]

참가 물질

4

반응물 2

HCID 222AmmoniaHCID 214326003-(3-Nitro-4-chlorobenzoyl)pyridine

생성물 1

HCID 214325873-(3-Nitro-4-aminobenzoyl)pyridine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A suspension of 63 g. (0.24 mol) of 3-(3-nitro-4-chlorobenzoyl)pyridine in 3 liters of a saturated solution of ammonia in ethanol was autoclaved at 100° C. for 24 hours. The mixture was concentrated in vacuo and the resulting residue dissolved in 1.5 liters of warm 5N HCl. The solution was cooled to room temperature and neutralized with concentrated ammonium hydroxide. The resulting product was collected as yellow-orange prisms, mp. 229° -230° C. (dimethylformamide-2-propanol).

후처리

  1. additionA suspension of 63 g
  2. concentrationThe mixture was concentrated in vacuo
  3. dissolutionthe resulting residue dissolved in 1.5 liters of warm 5N HCl
  4. customThe resulting product was collected as yellow-orange prisms, mp. 229° -230° C. (dimethylformamide-2-propanol)

출처 및 근거

ORD 기록
ord-cec53df07eca460888cad9af9ad2a29e
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04026936

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