Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 240034생성일: 2026년 10월 26일
2,2-Dimethyl-1,3-dioxane-4,6-dione → 6-(Trifluoromethoxy)-2-oxo-2H-chromene-3-carboxylic acid
https://huagongshe.com/reaction/240034
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| 반응물 | 2-Hydroxy-5-(trifluoromethoxy)benzaldehyde | HCID 1268058 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 6-(Trifluoromethoxy)-2-oxo-2H-chromene-3-carboxylic acid | HCID 10061868 | 50% |
반응 단계
5-trifluoromethoxy-salicylaldehyde (286.0 mg, 1.39 mmol) and Meldrum's acid (200 mg, 1.39 mmol) were combined in H2O (2 mL). The solution was stirred at 75° C. for 2 h. After cooling to room temperature, the precipitate was filtered and dried at suction to give 189.1 mg of 6-trifluoromethoxy-3-carboxy-coumarin in a 50% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08642788B2 |
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| 출처 데이터셋 | uspto-grants-2014_02 |
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| ORD ID | ord-75c7661c2c424a7abc926de33611af6d |
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| 출처 메모 | uspto-grants-2014_02 |
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