참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| 반응물 | 5-Iodosalicylaldehyde | HCID 252612 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 6-Iodo-3-carboxy-coumarin | HCID 18996405 | 69% |
반응 단계
5-iodosalicylaldehyde (344.2 mg, 1.39 mmol) and Meldrum's acid (200 mg, 1.39 mmol) were combined in H2O (2 mL). The solution was stirred at 75° C. for 2 h. After cooling to room temperature, the precipitate was filtered and dried at suction to give 302.0 mg of 6-iodo-3-carboxy-coumarin in 69% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08642788B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_02 |
|---|
| ORD ID | ord-fd89cebea6e1418f82f7f52836e62dc4 |
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| 출처 메모 | uspto-grants-2014_02 |
|---|
