N-(2-Hydroxyethyl)imidazole → 5-[1-(4-Chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-3-(2-imidazol-1-ylethyl)thiazolidine-2,4-dione
반응식
[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=[C:17]4[S:21][C:20](=[O:22])[NH:19][C:18]4=[O:23])=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:26]([F:29])([F:28])[F:27])[CH:3]=1.[N:30]1([CH2:35][CH2:36]O)[CH:34]=[CH:33][N:32]=[CH:31]1>>[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=[C:17]4[S:21][C:20](=[O:22])[N:19]([CH2:36][CH2:35][N:30]5[CH:34]=[CH:33][N:32]=[CH:31]5)[C:18]4=[O:23])=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:26]([F:27])([F:29])[F:28])[CH:3]=1참가 물질
3
실험 절차
5-[1-(4-Chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-3-(2-imidazol-1-ylethyl)thiazolidine-2,4-dione was prepared from 5-[1-(4-chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]thiazolidine-2,4-dione (from Example 1) and 2-imidazol-1-ylethanol following General Procedure J.
출처 및 근거
- ORD 기록
- ord-ff0db81e9d904d5882dd73a253498b33