1H-Indazole-5-carboxaldehyde → 1-(4-Bromo-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

반응식

[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Br)=[C:4]([C:10]([F:13])([F:12])[F:11])[CH:3]=1.[NH:14]1[C:22]2[C:17](=[CH:18][C:19]([CH:23]=[O:24])=[CH:20][CH:21]=2)[CH:16]=[N:15]1>>[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][N:14]2[C:22]3[C:17](=[CH:18][C:19]([CH:23]=[O:24])=[CH:20][CH:21]=3)[CH:16]=[N:15]2)=[C:4]([C:10]([F:13])([F:12])[F:11])[CH:3]=1

참가 물질

반응물 2

HCID 212506441H-Indazole-5-carboxaldehyde

HCID 534180314-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene

생성물 1

HCID 866545531-(4-Bromo-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

실험 절차

[4-Bromo-2-(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde was prepared from 4-bromo-2-(trifluoromethyl)benzyl bromide and 1H-indazol-5-carbaldehyde following General Procedure A.

출처 및 근거

ORD 기록: ord-b62730f77f9e4717a625b7e77ae4228c
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08796256B2

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