4-Chloro-2-(trifluoromethyl)benzyl bromide → 1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-iodo-1H-indazol-5-carbaldehyde

반응식

[I:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH:11]=[O:12])[CH:9]=2)[NH:4][N:3]=1.[Cl:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18]Br)=[C:16]([C:22]([F:25])([F:24])[F:23])[CH:15]=1>>[Cl:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18][N:4]2[C:5]3[C:10](=[CH:9][C:8]([CH:11]=[O:12])=[CH:7][CH:6]=3)[C:2]([I:1])=[N:3]2)=[C:16]([C:22]([F:23])([F:24])[F:25])[CH:15]=1

참가 물질

반응물 2

HCID 34925974-Chloro-2-(trifluoromethyl)benzyl bromide

HCID 178519380HCID 178519380, 화합물

생성물 1

HCID 866596981-[4-Chloro-2-(trifluoromethyl)benzyl]-3-iodo-1H-indazol-5-carbaldehyde

실험 절차

1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-iodo-1H-indazol-5-carbaldehyde was prepared from 3-iodo-1H-indazol-5-carbaldehyde and 4-chloro-2-(trifluoromethyl)benzyl bromide following General Procedure A.

출처 및 근거

ORD 기록: ord-6df8e8a4d49b4e0481e01583150705eb
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08796256B2

반응 노트

불러오는 중…