(2,4-Dioxo-1,3-thiazolidin-3-yl)acetic acid → HCID 58530506, 화합물

HRID 2401004

반응식

HRID 2401004 반응식
[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=O)=[CH:13][CH:14]=3)[C:9]([F:18])=[N:8]2)=[C:4]([C:21]([F:24])([F:23])[F:22])[CH:3]=1.[O:25]=[C:26]1[N:30]([CH2:31][C:32]([OH:34])=[O:33])[C:29](=[O:35])[CH2:28][S:27]1>>[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12](/[CH:16]=[C:28]4/[C:29](=[O:35])[N:30]([CH2:31][C:32]([OH:34])=[O:33])[C:26](=[O:25])[S:27]/4)=[CH:13][CH:14]=3)[C:9]([F:18])=[N:8]2)=[C:4]([C:21]([F:24])([F:23])[F:22])[CH:3]=1

참가 물질

3

반응물 2

HCID 2770836(2,4-Dioxo-1,3-thiazolidin-3-yl)acetic acidHCID 86659699HCID 86659699, 화합물

생성물 1

HCID 58530506HCID 58530506, 화합물

실험 절차

[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-fluoro-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid was prepared from 1-(4-chloro-2-trifluoromethyl-benzyl)-3-fluoro-1H-indazole-5-carbaldehyde (from Example 368) and (2,4-dioxothiazolidin-3-yl)acetic acid following General Procedure F.

출처 및 근거

ORD 기록
ord-7f8d971b5e314212b54071ac2df5f15f
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08796256B2

연결된 노트

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