(2,4-Dioxo-1,3-thiazolidin-3-yl)acetic acid → HCID 58530471, 화합물

HRID 2401017

반응식

HRID 2401017 반응식
[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=O)=[CH:13][CH:14]=3)[C:9]([C:18]#[N:19])=[N:8]2)=[C:4]([C:22]([F:25])([F:24])[F:23])[CH:3]=1.[O:26]=[C:27]1[N:31]([CH2:32][C:33]([OH:35])=[O:34])[C:30](=[O:36])[CH2:29][S:28]1>>[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12](/[CH:16]=[C:29]4/[C:30](=[O:36])[N:31]([CH2:32][C:33]([OH:35])=[O:34])[C:27](=[O:26])[S:28]/4)=[CH:13][CH:14]=3)[C:9]([C:18]#[N:19])=[N:8]2)=[C:4]([C:22]([F:24])([F:25])[F:23])[CH:3]=1

참가 물질

3

반응물 2

HCID 2770836(2,4-Dioxo-1,3-thiazolidin-3-yl)acetic acidHCID 86659712HCID 86659712, 화합물

생성물 1

HCID 58530471HCID 58530471, 화합물

실험 절차

[(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-3-cyano-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid was prepared from 1-(4-chloro-2-trifluoromethyl-benzyl)-5-formyl-1H-indazole-3-carbonitrile and (2,4-dioxothiazolidin-3-yl)-acetic acid following General Procedure F.

출처 및 근거

ORD 기록
ord-ca633d6ab7ac470eab3d46d7f4a6c4ab
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08796256B2

연결된 노트

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