Ammonium Hydroxide → 6-Aminopyridine-3-sulfonamide
반응식
Cl[C:2]1[N:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH4+:12].[OH-]>[Cl-].[Na+].O>[NH2:12][C:2]1[N:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1참가 물질
4
반응 조건
- 온도
- 110 °C
실험 절차
6-Chloropyridine-3-sulfonic acid amide (200 mg, 1 mmol) was placed in a sealed tube with 2 mL 28% aq. NH4OH and heated to 110° C. for 4 h. The mixture was diluted with brine and the title compound was collected as a solid (120 mg, 67%).
후처리
- customthe title compound was collected as a solid (120 mg, 67%)
출처 및 근거
- ORD 기록
- ord-99ba472de0b444089f6d7083198c06b6
- 출처 데이터셋
- uspto-grants-2014_08
- 특허 번호
- US08796313B2
반응 노트
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