Benzyl 3-(2-hydroxyethyl)piperidine-1-carboxylate → Benzyl 3-(2-bromoethyl)piperidine-1-carboxylate

HRID 2403810노트

반응식

HRID 2403810 반응식
[Br:1]CCC1CCCCN1C(OCC1C=CC=CC=1)=O.O[CH2:21][CH2:22][CH:23]1[CH2:28][CH2:27][CH2:26][N:25]([C:29]([O:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[O:30])[CH2:24]1>>[Br:1][CH2:21][CH2:22][CH:23]1[CH2:28][CH2:27][CH2:26][N:25]([C:29]([O:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[O:30])[CH2:24]1

참가 물질

3

반응물 2

HCID 13971207Benzyl 3-(2-hydroxyethyl)piperidine-1-carboxylateHCID 58306210Benzyl 2-(2-bromoethyl)piperidine-1-carboxylate

생성물 1

HCID 58306150Benzyl 3-(2-bromoethyl)piperidine-1-carboxylate

실험 절차

Prepared similarly to Intermediate 26 from phenylmethyl 3-(2-hydroxyethyl)-1-piperidinecarboxylate

출처 및 근거

ORD 기록
ord-11c511e770f64789b6cf6a59fdb0f9c3
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08802684B2

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