Phenylmethyl 4-(6-hydroxyhexyl)-1-piperidinecarboxylate → Phenylmethyl 4-(6-bromohexyl)-1-piperidinecarboxylate

반응식

[Br:1]CCCC1CCCCN1C(OCC1C=CC=CC=1)=O.O[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH:28]1[CH2:33][CH2:32][N:31]([C:34]([O:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[O:35])[CH2:30][CH2:29]1>>[Br:1][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH:28]1[CH2:33][CH2:32][N:31]([C:34]([O:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[O:35])[CH2:30][CH2:29]1

참가 물질

반응물 2

HCID 58306109Phenylmethyl 4-(6-hydroxyhexyl)-1-piperidinecarboxylate

HCID 58306190Benzyl 2-(3-bromopropyl)piperidine-1-carboxylate

생성물 1

HCID 58306218Phenylmethyl 4-(6-bromohexyl)-1-piperidinecarboxylate

실험 절차

Prepared similarly to Intermediate 30 from phenylmethyl 4-(6-hydroxyhexyl)-1-piperidinecarboxylate.

출처 및 근거

ORD 기록: ord-89a5d678bf1f4dd0a7aa87e8ac7d2a7f
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08802684B2

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