1-Iodopropane → 6-Amino-2-(butyloxy)-9-[4-(1-propyl-4-piperidinyl)butyl]-7,9-dihydro-8H-purin-8-one

반응식

[CH2:1]([O:5][C:6]1[N:14]=[C:13]2[C:9]([N:10]=[C:11]([O:25]C)[N:12]2[CH2:15][CH2:16][CH2:17][CH2:18][CH:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)=[C:8]([NH2:27])[N:7]=1)[CH2:2][CH2:3][CH3:4].I[CH2:29][CH2:30][CH3:31]>>[NH2:27][C:8]1[N:7]=[C:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])[N:14]=[C:13]2[C:9]=1[NH:10][C:11](=[O:25])[N:12]2[CH2:15][CH2:16][CH2:17][CH2:18][CH:19]1[CH2:20][CH2:21][N:22]([CH2:29][CH2:30][CH3:31])[CH2:23][CH2:24]1

참가 물질

반응물 2

HCID 336431-Iodopropane

HCID 583062222-(Butyloxy)-8-(methyloxy)-9-[4-(4-piperidinyl)butyl]-9H-purin-6-amine

생성물 1

HCID 448182186-Amino-2-(butyloxy)-9-[4-(1-propyl-4-piperidinyl)butyl]-7,9-dihydro-8H-purin-8-one

실험 절차

Prepared similarly to Example 82 from 2-(butyloxy)-8-(methyloxy)-9-[4-(4-piperidinyl)butyl]-9H-purin-6-amine and 1-iodopropane.

출처 및 근거

ORD 기록: ord-b44c4c6b670f431bbdda9b944f0d3197
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08802684B2

반응 노트

불러오는 중…