Tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate → HCID 178452896, 화합물
반응식
C([O:8][C:9]1[CH:14]=[CH:13][N:12]=[C:11]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:10]=1)C1C=CC=CC=1>CO.[Pd]>[OH:8][C:9]1[CH:14]=[CH:13][N:12]=[C:11]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:20])([CH3:19])[CH3:21])[CH:10]=1참가 물질
4
실험 절차
To a solution of tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate (5.89 g, 19.6 mmol) in methanol was added palladium on carbon (1.04 g, 0.981 mmol). After stirring under a hydrogen balloon at room temperature for 70 minutes, the solids were removed by filtration. The filtrate was concentrated under reduced pressure and solidified under high vacuum to provide the product (4.12 g, 99%) as white solid.
후처리
- customthe solids were removed by filtration
- concentrationThe filtrate was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-f8e0b6e7abb3461aa7b5e1fed25787b0
- 출처 데이터셋
- uspto-grants-2014_02
- 특허 번호
- US08648087B2
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