Benzyl isocyanate → HCID 24863360, 화합물

HRID 2405759노트

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HRID 2405759 반응식
[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[NH:7][CH:6]=[CH:5]2.[CH2:13]([N:20]=[C:21]=[O:22])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>CC(N(C)C)=O>[CH2:13]([NH:20][C:21]([NH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[NH:7][CH:6]=[CH:5]2)=[O:22])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

4

반응물 2

HCID 76639Benzyl isocyanateHCID 513420016-Amino-1,2-dihydroisoquinolin-1-one

생성물 1

HCID 24863360HCID 24863360, 화합물

시약·촉매·용매 1

HCID 31374Dimethylacetamide용매

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온도
60 °C

실험 절차

6-Amino-2H-isoquinolin-1-one (0.2 mmol, 39 mg) and benzyl isocyanate (0.2 mmol, 27 mg) were dissolved in 1 mL DMA. The mixture was allowed to stir at 60° C. overnight. The product was obtained by HPLC purification. MS (M+1) 294.

후처리

  1. customThe product was obtained by HPLC purification

출처 및 근거

ORD 기록
ord-6af916e923b44959990e43cbc3e1ffba
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08809326B2

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