Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Aminopiperidin-4-OL → 5-Cyclohexyl-N-(4-hydroxypiperidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Aminopiperidin-4-OL | HCID 12125645 | — |
| 반응물 | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| 생성물 | 5-Cyclohexyl-N-(4-hydroxypiperidin-1-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide | HCID 71294089 | — |
반응 단계
The title compound was synthesized in analogy to Example 1 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxylic acid and 1-amino-4-piperidinol (CAN 79414-82-7) as starting materials; LC-MS (UV peak area/ESI) 96.4%, 402.1991 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08648099B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-2eeb7b93cccc47458664bd6c7721f77c |
| 출처 메모 | uspto-grants-2014_02 |