Ammonia → 5-(3-Methoxyphenyl)-1,2,4-triazin-3-amine

HRID 2407082노트

반응식

HRID 2407082 반응식
CS([C:5]1[N:6]=[N:7][CH:8]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=2)[N:10]=1)(=O)=O.[NH3:19].C1COCC1>>[CH3:18][O:17][C:13]1[CH:12]=[C:11]([C:9]2[N:10]=[C:5]([NH2:19])[N:6]=[N:7][CH:8]=2)[CH:16]=[CH:15][CH:14]=1

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 8028TetrahydrofuranHCID 67363595HCID 67363595, 화합물

생성물 1

HCID 71760865-(3-Methoxyphenyl)-1,2,4-triazin-3-amine수율 45%

실험 절차

5-(3-Methoxyphenyl)-1,2,4-triazin-3-amine (0.31 g, 45%) was prepared from 3-(methylsulfonyl)-5-(3-methoxyphenyl)-1,2,4-triazine (0.90 g, 3.39 mmol) and 0.5 M ammonia in THF (50 mL, 25.0 mmol) according to the general procedure of Preparation 2.

후처리

  1. customaccording to the general procedure of Preparation 2

출처 및 근거

ORD 기록
ord-77481477eb6940c5bd27c34028138ef4
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08809525B2

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