2-(3,5-Difluorophenyl)-2-oxoacetaldehyde → HCID 67365291, 화합물

반응식

[NH:1]([C:3]([S:5][CH3:6])=[NH:4])[NH2:2].[F:7][C:8]1[CH:9]=[C:10]([C:15](=O)[CH:16]=O)[CH:11]=[C:12]([F:14])[CH:13]=1>>[CH3:6][S:5][C:3]1[N:1]=[N:2][CH:16]=[C:15]([C:10]2[CH:9]=[C:8]([F:7])[CH:13]=[C:12]([F:14])[CH:11]=2)[N:4]=1

참가 물질

반응물 2

HCID 187847012-(3,5-Difluorophenyl)-2-oxoacetaldehyde

HCID 178504051Methyl hydrazinecarbimidothioate

생성물 1

HCID 67365291HCID 67365291, 화합물수율 80%

실험 절차

3-(methylsulfanyl)-5-(3,5-difluorophenyl)-1,2,4-triazine (28 g, 80.0%) was prepared from methyl hydrazine carbimidothioate (20.68 g, 197.4 mmol) and 2-(3,5-difluorophenyl)-2-oxoacetaldehyde (25 g, 147.0 mmol) according to the general procedure of Preparation 2.

후처리

customaccording to the general procedure of Preparation 2

출처 및 근거

ORD 기록: ord-abb464f8b92d43a282bb3435d245e5c4
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08809525B2

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