3-Fluorophenylboronic acid → HCID 67363642, 화합물

HRID 2407120노트

반응식

HRID 2407120 반응식
Br[C:2]1[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[F:15][C:16]1[CH:17]=[C:18](B(O)O)[CH:19]=[CH:20][CH:21]=1>>[F:15][C:16]1[CH:21]=[C:20]([C:2]2[N:7]=[N:6][C:5]([NH2:8])=[N:4][C:3]=2[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:19]=[CH:18][CH:17]=1

참가 물질

3

반응물 2

HCID 27339863-Fluorophenylboronic acidHCID 866761146-Bromo-5-phenyl-1,2,4-triazin-3-amine

생성물 1

HCID 67363642HCID 67363642, 화합물수율 62%

실험 절차

6-(3-Fluorophenyl)-5-phenyl-1,2,4-triazin-3-amine (49 mg, 62%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (75 mg, 0.299 mmol) and 3-fluorophenylboronic acid (48.1 mg, 0.344 mmol) according to the general procedure of Example 1.

출처 및 근거

ORD 기록
ord-0ba336a7983c4226b9c4dd2604c79b2d
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08809525B2

반응 노트

불러오는 중…