Trifluoroacetic acid → HCID 86659060, 화합물
반응식
[OH:1][C:2]1([CH2:20][NH:21]C(=O)OC(C)(C)C)[CH2:7][CH2:6][N:5]([CH2:8][C:9]2[S:13][C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)=[N:11][CH:10]=2)[CH2:4][CH2:3]1.[F:29][C:30]([F:35])([F:34])[C:31]([OH:33])=[O:32]>ClCCl>[F:29][C:30]([F:35])([F:34])[C:31]([OH:33])=[O:32].[F:29][C:30]([F:35])([F:34])[C:31]([OH:33])=[O:32].[NH2:21][CH2:20][C:2]1([OH:1])[CH2:7][CH2:6][N:5]([CH2:8][C:9]2[S:13][C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)=[N:11][CH:10]=2)[CH2:4][CH2:3]1참가 물질
4
실험 절차
A solution of the compound prepared in Example 252 (0.108 g) in dichloromethane (1.3 mL) was treated with trifluoroacetic acid (0.3 mL) at room temperature for 18 hours. The solvent was evaporated in vacuo and the residue was azeotroped from toluene twice to obtain the title compound (0.104 g) having the following physical data.
후처리
- customThe solvent was evaporated in vacuo