2-(Pyridin-2-yl)-1,3-thiazole-5-carbaldehyde → HCID 66989601, 화합물

반응식

[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C@@H:17]2[CH2:22][CH2:21][NH:20][CH2:19][C@H:18]2[OH:23])=[O:14])[CH:3]=1.[N:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[C:30]1[S:31][C:32]([CH:35]=O)=[CH:33][N:34]=1>>[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[C:6]([O:10][CH2:11][CH3:12])[N:5]=[C:4]([C:13]([NH:15][CH2:16][C@@H:17]2[CH2:22][CH2:21][N:20]([CH2:35][C:32]3[S:31][C:30]([C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][N:24]=4)=[N:34][CH:33]=3)[CH2:19][C@H:18]2[OH:23])=[O:14])[CH:3]=1

참가 물질

반응물 2

HCID 534037722-(Pyridin-2-yl)-1,3-thiazole-5-carbaldehyde

HCID 66990398HCID 66990398, 화합물

생성물 1

HCID 66989601HCID 66989601, 화합물

실험 절차

According to the same procedure described in Example 101, starting with the compound prepared in Example 268 and the compound prepared in Example 139, the title compound having the following physical data was obtained.

출처 및 근거

ORD 기록: ord-59b674022f794c57aa84c84f44f07086
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08809538B2

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