2-Methoxyaniline → 4-methoxy-N-(2-methoxyphenyl)benzenesulfonamide

반응식

[CH3:1][O:2][C:3]1[C:4]([NH2:9])=[CH:5][CH:6]=[CH:7][CH:8]=1.[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1>>[CH3:10][O:11][C:12]1[CH:13]=[CH:14][C:15]([S:18]([NH:9][C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[O:2][CH3:1])(=[O:20])=[O:19])=[CH:16][CH:17]=1

참가 물질

반응물 2

HCID 70002-Methoxyaniline

HCID 74014-Methoxybenzenesulfonyl chloride

생성물 1

HCID 7434174-methoxy-N-(2-methoxyphenyl)benzenesulfonamide수율 90.1%

실험 절차

Using o-anisidine (1.0 ml, 8.55 mmol) and 4-methoxybenzenesulfonyl chloride (1.78 g, 8.55 mmol), the procedure of Reference Example 2 was repeated to obtain 2.26 g (90.1%) of the title compound in the form of colorless powder.

출처 및 근거

ORD 기록: ord-80f67fcb3ee14ef2b196db2ad72d47b4
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05728835

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