Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 2-Acetoxypropionic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Lactic Acid | HCID 612 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-Acetoxypropionic Acid | HCID 79041 | 92% |
반응 단계
Reflux a mixture of 2-hydroxy-propionic acid (480 ml, 85% in water) and sulfuric acid (2 mL) in acetic acid (2500 mL) and toluene (300 mL) for overnight. After removal of solvent under vacuum, purify the residue by distillation to give 2-acetoxy-propionic acid (550 g, 92%) as colorless oil. 1H NMR (CDCl3, 400 MHz): δ 9.27 (brs, 1H), 5.10 (m, 1H), 2.13 (s, 3H), 1.53 (d, J=7.2, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08648081B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-454818cf5b8a4bdebc359436e7990c79 |
| 출처 메모 | uspto-grants-2014_02 |