Chloroacetonitrile → 3-Amino-5-phenylselenophene-2-carbonitrile

HRID 2408953노트

반응식

HRID 2408953 반응식
Cl[C:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[CH:3][C:4]#[N:5].[Se-2:12].[Na+].[Na+].Cl[CH2:16][C:17]#[N:18]>>[NH2:5][C:4]1[CH:3]=[C:2]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[Se:12][C:16]=1[C:17]#[N:18]

참가 물질

4

반응물 3

HCID 7856ChloroacetonitrileHCID 73973Sodium selenideHCID 27775113-Chloro-3-phenyl-2-propenenitrile

생성물 1

HCID 866468883-Amino-5-phenylselenophene-2-carbonitrile수율 53%

실험 절차

The reaction of 3-chloro-3-phenylprop-2-enenitrile, sodium selenide and chloroacetonitrile as described earlier gave the product as a brown color solid (4.8 g, 53%), mp 162-164° C. (decomp). 1H NMR (400 MHz, CDCl3): δ 7.46-7.49 (2H, m), 7.37-7.39 (3H, m), 7.01 (1H, s), 4.55 (2H, br s).

출처 및 근거

ORD 기록
ord-9478aa3fdc764589bb16a3f3187981d6
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08815879B2

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