1-Bromo-2-methylpropane → HCID 58293149, 화합물

HRID 2410342노트

반응식

HRID 2410342 반응식
[F:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.[CH2:9](Br)[CH:10]([CH3:12])[CH3:11].FC(F)(F)S(OCC(F)(F)F)(=O)=O>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH2:9][CH:10]([CH3:12])[CH3:11])[CH:3]=1

참가 물질

4

반응물 3

HCID 65551-Bromo-2-methylpropaneHCID 97433-FluorophenolHCID 803662,2,2-Trifluoroethyl trifluoromethanesulfonate

생성물 1

HCID 58293149HCID 58293149, 화합물

실험 절차

The title compound was prepared according to the procedure described in Step 7 of EXAMPLE 7 using 3-fluorophenol and isobutyl bromide instead of methyl 4-[(4-{2-[(4-hydroxy-1,2-benzisoxazol-3-yl)oxy]ethyl}piperidin-1-yl)methyl]tetrahydro-2H-pyran-4-carboxylate and 2,2,2-trifluoroethyl trifluoromethanesulfonate.

출처 및 근거

ORD 기록
ord-a57818a14e2c408497db3e028e109627
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08816090B2

반응 노트

불러오는 중…