1,3-Propanesultam → HCID 71252648, 화합물

HRID 2411313노트

반응식

HRID 2411313 반응식
[Br:1][C:2]1[CH:11]=[C:10]([CH2:12]Br)[CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].[S:14]1(=[O:20])(=[O:19])[CH2:18][CH2:17][CH2:16][NH:15]1>>[Br:1][C:2]1[CH:11]=[C:10]([CH2:12][N:15]2[CH2:16][CH2:17][CH2:18][S:14]2(=[O:20])=[O:19])[CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5]

참가 물질

3

반응물 2

HCID 6421571,3-PropanesultamHCID 19806367Methyl 2-bromo-4-(bromomethyl)benzoate

생성물 1

HCID 71252648HCID 71252648, 화합물수율 55.2%

실험 절차

Using methyl 2-bromo-4-bromomethylbenzoate (500 mg) and isothiazolidine 1,1-dioxide (216 mg) and by the reaction and treatment in the same manner as in Preparation Example 42, the title compound (312 mg) was obtained.

후처리

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 42

출처 및 근거

ORD 기록
ord-012f19333b294188843ac91fa2a4de5d
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08816079B2

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