4-Methyloxybenzyl chloride → 5-Isopropyl-3-(4-methoxybenzyl)imidazolidine-2,4-dione

반응식

[CH:1]([CH:4]1[NH:8][C:7](=[O:9])[NH:6][C:5]1=[O:10])([CH3:3])[CH3:2].[CH3:11][O:12][C:13]1[CH:20]=[CH:19][C:16]([CH2:17]Cl)=[CH:15][CH:14]=1>>[CH:1]([CH:4]1[NH:8][C:7](=[O:9])[N:6]([CH2:17][C:16]2[CH:19]=[CH:20][C:13]([O:12][CH3:11])=[CH:14][CH:15]=2)[C:5]1=[O:10])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 699934-Methyloxybenzyl chloride

HCID 1030335-Isopropylhydantoin

생성물 1

HCID 712528645-Isopropyl-3-(4-methoxybenzyl)imidazolidine-2,4-dione

실험 절차

Using 5-isopropylimidazolidine-2,4-dione (2.00 g) and 4-methoxybenzyl chloride (2.29 mL) and by the reaction and treatment in the same manner as in Preparation Example 51, the title compound (2.72 g) was obtained.

후처리

customby the reaction and treatment in the same manner
customas in Preparation Example 51

출처 및 근거

ORD 기록: ord-189474c7e3ac4500bdba415a95c91613
출처 데이터셋: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08816079B2

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