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1-(5-Ethyl-3-methylpyridin-2-yl)piperazine → HCID 86676772, 화합물

HRID 2411377
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인쇄 미리보기

반응식

HRID 2411377 반응식
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([CH3:11])[N:3]=1.[CH2:12]([C:14]1[CH:15]=[C:16]([CH3:26])[C:17]([N:20]2[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]2)=[N:18][CH:19]=1)[CH3:13]>>[Br:1][C:2]1[N:3]=[C:4]([CH3:11])[C:5]([C:6]([N:23]2[CH2:24][CH2:25][N:20]([C:17]3[C:16]([CH3:26])=[CH:15][C:14]([CH2:12][CH3:13])=[CH:19][N:18]=3)[CH2:21][CH2:22]2)=[O:8])=[CH:9][CH:10]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

3

반응물 2

HCID 584845781-(5-Ethyl-3-methylpyridin-2-yl)piperazineHCID 716915676-BroMo-2-Methyl-nicotinic acid

생성물 1

HCID 86676772HCID 86676772, 화합물수율 55.3%

실험 절차

Using 6-bromo-2-methylnicotinic acid (675 mg) and 1-(5-ethyl-3-methylpyridin-2-yl)piperazine (611 mg) described in Preparation Example 81 and by the reaction and treatment in the same manner as in Preparation Example 111, the title compound (664 mg) was obtained.

후처리

  1. customdescribed in Preparation Example 81 and by the reaction and treatment in the same manner as in Preparation Example 111

출처 및 근거

ORD 기록
ord-cb5b380073784858b412fff030a14dbb
출처 데이터셋
이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트
uspto-grants-2014_08
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US08816079B2

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