Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2,4,6-Trimethylphenyl)piperazine → [4-(1,1-Dioxo-1lambda6-isothiazolidin-2-yl)phenyl][4-(2,4,6-trimethylphenyl)piperazin-1-yl]methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2,4,6-Trimethylphenyl)piperazine | HCID 2760822 | — |
| 반응물 | 4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzoic acid | HCID 6625011 | — |
| 생성물 | [4-(1,1-Dioxo-1lambda6-isothiazolidin-2-yl)phenyl][4-(2,4,6-trimethylphenyl)piperazin-1-yl]methanone | HCID 71252840 | 23% |
반응 단계
Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoic acid (253 mg) described in Preparation Example 16 and 1-(2,4,6-trimethylphenyl)piperazine (215 mg) and by the reaction and treatment in the same manner as in Example 87, the title compound (103 mg) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08816079B2 |
| 출처 데이터셋 | uspto-grants-2014_08 |
| ORD ID | ord-af5131c153af494fa7170d61c24f4651 |
| 출처 메모 | uspto-grants-2014_08 |