1-(2,4-Xylyl)piperazine → HCID 71251911, 화합물

HRID 2411848노트

반응식

HRID 2411848 반응식
[N:1]1([C:10]2[CH:19]=[CH:18][C:13]([C:14]([O:16]C)=O)=[CH:12][CH:11]=2)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[CH3:20][C:21]1[CH:26]=[C:25]([CH3:27])[CH:24]=[CH:23][C:22]=1[N:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[N:1]1([C:10]2[CH:11]=[CH:12][C:13]([C:14]([N:31]3[CH2:32][CH2:33][N:28]([C:22]4[CH:23]=[CH:24][C:25]([CH3:27])=[CH:26][C:21]=4[CH3:20])[CH2:29][CH2:30]3)=[O:16])=[CH:18][CH:19]=2)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1

참가 물질

3

반응물 2

HCID 705441-(2,4-Xylyl)piperazineHCID 5328451HCID 5328451, 화합물

생성물 1

HCID 71251911HCID 71251911, 화합물수율 55.6%

실험 절차

Using methyl 4-(benzimidazol-1-yl)benzoate (126 mg) and 1-(2,4-dimethylphenyl)piperazine (95 mg) and by the reaction and treatment in the same manner as in Example 109, the title compound (114 mg) was obtained.

후처리

  1. customby the reaction and treatment in the same manner as in Example 109

출처 및 근거

ORD 기록
ord-9a6350d9ad7a438cab56df856760c36c
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08816079B2

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