4-Methoxybenzenesulfonyl chloride → N-(2-cyanophenyl)-4-methoxybenzenesulfonamide

HRID 2412

반응식

HRID 2412 반응식
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1>>[C:4]([C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[NH:1][S:18]([C:15]1[CH:14]=[CH:13][C:12]([O:11][CH3:10])=[CH:17][CH:16]=1)(=[O:20])=[O:19])#[N:5]

참가 물질

3

반응물 2

HCID 74014-Methoxybenzenesulfonyl chlorideHCID 729132-Aminobenzonitrile

생성물 1

HCID 669671N-(2-cyanophenyl)-4-methoxybenzenesulfonamide수율 63.7%

실험 절차

Using 2-aminobenzonitrile (1.03 g, 8.55 mmol) and 4-methoxybenzenesulfonyl chloride (1.78 g, 8.55 mmol), the procedure of Reference Example 2 was repeated to obtain 1.57 g (63.7%) of the title compound in the form of colorless solid.

출처 및 근거

ORD 기록
ord-884108655568491b9b7065118f5c820d
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05728835

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