HCID 131714074, 화합물 → H-Pro-Trp-Met-NH2

HRID 2412323노트

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HRID 2412323 반응식
[N:1]1(C(OC(C)(C)C)=O)[CH2:30][CH2:29][CH2:28][C@H:2]1[C:3]([NH:5][C@H:6]([C:17]([NH:19][C@H:20]([C:25]([NH2:27])=[O:26])[CH2:21][CH2:22][S:23][CH3:24])=[O:18])[CH2:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:10][CH:9]=1)=[O:4]>C(O)C>[NH:1]1[CH2:30][CH2:29][CH2:28][C@H:2]1[C:3]([NH:5][C@H:6]([C:17]([NH:19][C@H:20]([C:25]([NH2:27])=[O:26])[CH2:21][CH2:22][S:23][CH3:24])=[O:18])[CH2:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[NH:10][CH:9]=1)=[O:4]

참가 물질

3

반응물 1

HCID 131714074HCID 131714074, 화합물

생성물 1

HCID 13306573H-Pro-Trp-Met-NH2수율 86.8%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Starting from 3.722 g (7 mmol) of Boc-Pro-Trp-Met-NH2 (VI) and operating as in Step 2 of Example 1, 2.621 g (80% yield) of VII were obtained from absolute ethyl alcohol; [α]D20 =-23.0° (c=1 MeOH); RfC 0.41; E1.2 0.76.

출처 및 근거

ORD 기록
ord-7747a47ad94a47669a06f234635562cd
출처 데이터셋
uspto-grants-1985_01
특허 번호
US04491541

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