p-Toluenesulfonate → Thieno[2,3-c]pyridin-4-ol

반응식

[S:1]([C:5]1[CH:11]=CC(C)=CC=1)([O-])(=O)=O.O=C1[CH2:18][N:17](S(C2C=CC(C)=CC=2)(=O)=O)[CH2:16][C:15]2C=CSC1=2.[CH2:32]([OH:34])[CH3:33].C1CCCCC1>>[OH:34][C:32]1[CH:18]=[N:17][CH:16]=[C:15]2[S:1][CH:5]=[CH:11][C:33]=12

참가 물질

반응물 3

HCID 85570p-Toluenesulfonate

HCID 12751998HCID 12751998, 화합물

HCID 21585052HCID 21585052, 화합물

생성물 1

HCID 13019694Thieno[2,3-c]pyridin-4-ol수율 78%

실험 절차

This compound is prepared according to the procedure of Example 1(c), from the tosylate described in (b) above (Yield: 78%). White crystals; M.p.=206° C. (ethanol-cyclohexane).

후처리

customThis compound is prepared

출처 및 근거

ORD 기록: ord-0b60415d113547c79f0fbde34d41ea69
출처 데이터셋: uspto-grants-1985_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04496568

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