Acetic Acid → HCID 54127815, 화합물

HRID 2413451노트

반응식

HRID 2413451 반응식
C[O-].[Na+].[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=O.[CH3:18][C:19]([C:21]1[CH:22]=[CH:23][C:24]([OH:27])=[CH:25][CH:26]=1)=O.[Cl-].C1([PH+](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(O)(=O)C>CO.C(O)C>[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=[CH:18][CH2:19][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=1

참가 물질

7

반응물 4

HCID 176Acetic AcidHCID 10942334Sodium MethoxideHCID 13090787HCID 13090787, 화합물HCID 86741956HCID 86741956, 화합물

생성물 1

HCID 54127815HCID 54127815, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 887Methanol용매

반응 조건

온도
20 °C

실험 절차

36 ml of a 15% strength solution of sodium methylate in methanol were added to 11 g of 3,7-dichloro-8-formylquinoline and 21.6 g of 4-hydroxyacetophenone-triphenylphosphonium chloride in 150 ml of ethanol. The mixture was stirred for 21/2 hours at 20° C., after which 3 ml of glacial acetic acid were added and the precipitate was filtered off under suction, washed with water and dried.

후처리

  1. filtrationthe precipitate was filtered off under suction
  2. washwashed with water
  3. customdried

출처 및 근거

ORD 기록
ord-e7e2b04f662f42a8a83157e311725dcc
출처 데이터셋
uspto-grants-1988_01
특허 번호
US04717416

반응 노트

불러오는 중…