Salicylic Acid → 2,3-Dihydroxybenzoic Acid

반응식

C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)[OH:4].C(N)(=O)C1CC=CNC=1.[C:23]([OH:32])(=[O:31])[C:24]1[C:25](=[CH:27][CH:28]=[CH:29][CH:30]=1)[OH:26]>>[OH:26][C:25]1[C:27]([OH:4])=[CH:28][CH:29]=[CH:30][C:24]=1[C:23]([OH:32])=[O:31]

참가 물질

반응물 3

HCID 338Salicylic Acid

HCID 31348Citrate

HCID 135865461,4-Dihydropyridine-3-carboxamide

생성물 1

HCID 192,3-Dihydroxybenzoic Acid

실험 절차

The process is conducted in a manner similar to that described in Example 1 hereinbefore, except that 1 ml of the citrate buffer, 1 mg of cellulose modified with 1,4-dihydronicotinamide and 0.03 mg of 9-methyl-phenazium methyl sulfate and 0.3 mg. of salicylic acid are used. As a result, 0.28 mg. of 2,3-dihydroxybenzoic acid is obtained (95% as calculated for the starting compound) having m.p. 203°-204° C. The composition, in %, is as follows:

출처 및 근거

ORD 기록: ord-16114f7a6e4547608b8431ae2ec21df9
출처 데이터셋: uspto-grants-1988_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04718994

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