[3-Propyl-6-(trifluoromethyl)-benzothiophen-2-yl]methanol → 3-[2-Methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propionyl]phenyl]propionic acid
반응식
[CH3:1][C:2]1[CH:7]=[C:6]([C:8](=[O:27])[CH2:9][CH2:10][C:11]2[S:12][C:13]3[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:14]=3[C:15]=2[CH2:16][CH2:17][CH3:18])[CH:5]=[CH:4][C:3]=1[CH2:28][CH2:29][C:30]([O:32]C)=[O:31].C(C1C2C=CC(C(F)(F)F)=CC=2SC=1CO)CC>>[CH3:1][C:2]1[CH:7]=[C:6]([C:8](=[O:27])[CH2:9][CH2:10][C:11]2[S:12][C:13]3[CH:22]=[C:21]([C:23]([F:24])([F:25])[F:26])[CH:20]=[CH:19][C:14]=3[C:15]=2[CH2:16][CH2:17][CH3:18])[CH:5]=[CH:4][C:3]=1[CH2:28][CH2:29][C:30]([OH:32])=[O:31]참가 물질
3
반응물 2
생성물 1
실험 절차
The titled compound was prepared from the above-mentioned methyl 3-[2-methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propionyl]phenyl]propionate (38 mg, 0.08 mmol) in a procedure similar to that of Example (3) as a white crystal (14 mg, yield 66%).
출처 및 근거
- ORD 기록
- ord-8b336d26077b43d69588305524011ba5
- 출처 데이터셋
- uspto-grants-2014_02
- 특허 번호
- US08648208B2
반응 노트
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