2-Methoxyaniline → 4-((2-Methoxyphenyl)sulfamoyl)benzoic acid

반응식

[CH3:1][O:2][C:3]1[C:4]([NH2:9])=[CH:5][CH:6]=[CH:7][CH:8]=1.Cl[S:11]([C:14]1[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][CH:15]=1)(=[O:13])=[O:12]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][S:11]([C:14]1[CH:15]=[CH:16][C:17]([C:18]([OH:20])=[O:19])=[CH:21][CH:22]=1)(=[O:13])=[O:12]

참가 물질

반응물 2

HCID 70002-Methoxyaniline

HCID 823854-(Chlorosulfonyl)benzoic acid

생성물 1

HCID 23335054-((2-Methoxyphenyl)sulfamoyl)benzoic acid수율 95.7%

실험 절차

Using o-anisidine (0.585 ml, 5.0 mmol) and 4-(chlorosulfonyl)benzoic acid (1.15 g, 5.0 mmol), the procedure of Reference Example 2 was repeated to obtain 1.47 g (95.5%) of the title compound in the form of pink powder.

출처 및 근거

ORD 기록: ord-bcfcdbed56674c439cbfcd16edd11134
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05728835

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