Isopropylamine → HCID 22644575, 화합물

반응식

[Br:1][CH:2]1[N:6](C(C)C)[C:5]([C:10]([OH:12])=O)=[CH:4][S:3]1.C(N1C=CN=C1)(N1C=CN=C1)=O.[CH:25]([NH2:28])([CH3:27])[CH3:26]>>[Br:1][C:2]1[S:3][CH:4]=[C:5]([C:10]([NH:28][CH:25]([CH3:27])[CH3:26])=[O:12])[N:6]=1

참가 물질

반응물 3

HCID 6363Isopropylamine

HCID 682631,1'-Carbonyldiimidazole

HCID 22644605HCID 22644605, 화합물

생성물 1

HCID 22644575HCID 22644575, 화합물

실험 절차

The product was prepared from 2-bromo-N-(1-methylethyl)-1,3-thiazole-4-carboxylic acid (WO 9848799) (0.77 g), carbonyldiimidazole (0.66 g) and isopropylamine (0.24 g) using the method of example 115 step (i). Yield 0.82 g.

출처 및 근거

ORD 기록: ord-ed6dad694c1e40f9a43cc36eaf2816f6
출처 데이터셋: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06812226B2

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