HCID 10910039, 화합물 → HCID 60122358, 화합물

반응식

CC1OC(CCC(Cl)=O)=CC=1.[C:12]([O:16][C:17]([NH:19][CH:20]([CH2:24][C:25]1[O:26][C:27]([CH3:30])=[CH:28][CH:29]=1)[C:21]([OH:23])=[O:22])=[O:18])([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17]([NH:19][C@@H:20]([CH2:24][C:25]1[O:26][C:27]([CH3:30])=[CH:28][CH:29]=1)[C:21]([OH:23])=[O:22])=[O:18])([CH3:15])([CH3:14])[CH3:13]

참가 물질

반응물 2

HCID 10910039HCID 10910039, 화합물

HCID 22645440HCID 22645440, 화합물

생성물 1

HCID 60122358HCID 60122358, 화합물

실험 절차

3-(5-Methyl-furan-2-yl)-propionyl chloride (H. Kotsuki et al., Bull. Chem. Soc. Jpn., 1984, 57, 3339) is converted to (S) 2-(tert-butoxycarbonylamino)-3-(5-methyl-furan-2-yl)-propionic acid according to the Evans amino acid protocol (J. Am. Chem. Soc. 1990, 112, 4011).

출처 및 근거

ORD 기록: ord-955344f4595e4b3193bb995bad42c890
출처 데이터셋: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06812237B2

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