Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → 1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-ylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-Aminobenzonitrile | HCID 72913 | — |
| 반응물 | 2-(1-Benzyl-pyrrolidin-2-ylideneamino)benzonitrile | HCID 758406 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 생성물 | 1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-ylamine | HCID 711989 | — |
| 생성물 | HCID 178420813 | HCID 178420813 | — |
반응 단계
Pyrroloquinoline compounds were synthesized as follows. The compound 1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-ylamine was prepared from the cyclization of an amidine derivative, 2-(1-benzyl-pyrrolidin-2-ylideneamino)benzonitrile, which was synthesized by condensing an anthranilonitrile and 1-benzyl-2-pyrrolidione. This compound was then reacted with potassium tert-butoxide or sodium hydride and the corresponding alkyl chloride or acyl chloride (FIG. 6).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06815442B2 |
| 출처 데이터셋 | uspto-grants-2004_11 |
| ORD ID | ord-a4925147f81146e2b5c9171157dfd38a |
| 출처 메모 | uspto-grants-2004_11 |