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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2415311생성일: 2026년 10월 27일

2-(4-Methoxyphenyl)-1,1-dimethylethylamine → N-[2-Hydroxy-3-(2-chlorophenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

https://huagongshe.com/reaction/2415311

반응식

참여 물질

역할이름HCID투입량
반응물2-(4-Methoxyphenyl)-1,1-dimethylethylamineHCID 91892—
반응물2-(2-Chlorophenoxymethyl)oxiraneHCID 137500—
생성물N-[2-Hydroxy-3-(2-chlorophenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine HydrochlorideHCID 22640862139.4%

반응 단계

Using the method of Example 25, supra, 2-chlorophenyl glycidyl ether (1.0 mmol) and 1,1-dimethyl-2-(4-methoxyphenyl)ethylamine (1.25 mmol) yielded 279 mg of the title compound as a white solid: GC/EI-MS, m/z (rel. int.) 348 (M−15, 5), 245 (21), 244 (100), 242 (100), 163 (29), 121 (82), 114 (24), 77 (21), 71 (44), 70 (56), 58 (24).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06818660B2
출처 데이터셋uspto-grants-2004_11
ORD IDord-60a7cc15830447aeae09185314df44f0
출처 메모uspto-grants-2004_11