참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | (2E)-3-(4-(methoxycarbonyl)phenyl)prop-2-enoic acid | HCID 1472795 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | (2E)-2-Benzylidenebutanedioic Acid | HCID 820629 | — |
반응 단계
A solution of (E)-4-carbomethoxycinnamic acid (5.09 g, 24.7 mmol) was dissolved in dry THF (25 mL) and treated under an argon atmosphere with oxalyl chloride (3.00 mL, 34.4 mmol) and a drop of dry DMF. After heating at 50° C. for 2 hours, the reaction mixture was concentrated in vacuo to yield the acid chloride of (E)-carboxymethyl cinnamic acid as a tan solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06818646B2 |
|---|
| 출처 데이터셋 | uspto-grants-2004_11 |
|---|
| ORD ID | ord-110ef525cb0e443b9b036957dddc89af |
|---|
| 출처 메모 | uspto-grants-2004_11 |
|---|
