Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzamide → n-(4,7-Dichloroquinolin-2-yl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzamide | HCID 2331 | — |
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | 4,7-Dichloroquinoline 1-oxide | HCID 280096 | — |
| 생성물 | n-(4,7-Dichloroquinolin-2-yl)benzamide | HCID 22641855 | — |
반응 단계
A mixture of example 289A (10.0 g, 46.7 mmol) and benzoyl chloride (23.5 g, 168 mmol) and benzamide (5.9 g, 49.1 mmol) was heated at 180° C. for 6 hours, cooled to room temperature, filtered. Yellow solid as washed with large quantity of water and ethyl acetate (20 mL) and dried under vacuum. MS (ESI(+)Q1MS m/z 318 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06818772B2 |
| 출처 데이터셋 | uspto-grants-2004_11 |
| ORD ID | ord-85b015ad3d3f45328b92e2cccd4524f9 |
| 출처 메모 | uspto-grants-2004_11 |