4-(1H-Pyrazol-1-yl)benzaldehyde → (2E)-3-[4-(1-Methyl-1H-pyrazol-3-yl)phenyl]-2-propenal

HRID 2416476노트

반응식

HRID 2416476 반응식
[CH3:1][N:2]1[CH:6]=[CH:5][C:4]([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=2)=[N:3]1.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[CH3:1][N:2]1[CH:6]=[CH:5][C:4]([C:7]2[CH:14]=[CH:13][C:10](/[CH:11]=[CH:23]/[CH:24]=[O:25])=[CH:9][CH:8]=2)=[N:3]1

참가 물질

3

반응물 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 105355454-(1-METHYL-1H-PYRAZOL-3-YL)BENZALDEHYDE

생성물 1

HCID 22630993(2E)-3-[4-(1-Methyl-1H-pyrazol-3-yl)phenyl]-2-propenal

실험 절차

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(1-methyl-1H-pyrazol-3-yl)benzaldehyde (prepared as described in J. Med. Chem. 1998, 41, 2390) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 213 (M+H)+.

출처 및 근거

ORD 기록
ord-4a6493b6df8f4fe7bb84623c014fedcb
출처 데이터셋
uspto-grants-2004_11
특허 번호
US06825170B2

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