4-(1H-Pyrazol-1-yl)benzaldehyde → (2E)-3-[6-(1H-Pyrazol-1-yl)-2-pyridinyl]-2-propenal

HRID 2416481노트

반응식

HRID 2416481 반응식
[N:1]1([C:6]2[N:11]=[C:10]([CH:12]=O)[CH:9]=[CH:8][CH:7]=2)[CH:5]=[CH:4][CH:3]=[N:2]1.N1(C2C=C[C:22]([CH:23]=[O:24])=CC=2)C=CC=N1>>[N:1]1([C:6]2[N:11]=[C:10](/[CH:12]=[CH:22]/[CH:23]=[O:24])[CH:9]=[CH:8][CH:7]=2)[CH:5]=[CH:4][CH:3]=[N:2]1

참가 물질

3

반응물 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 105114076-(1H-Pyrazol-1-yl)-2-pyridinecarboxaldehyde

생성물 1

HCID 22630972(2E)-3-[6-(1H-Pyrazol-1-yl)-2-pyridinyl]-2-propenal

실험 절차

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 6-(1H-pyrazol-1-yl)-2-pyridinecarboxaldehyde (prepared as described in J. Med. Chem. 1998, 41, 5070) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 200 (M+H)+.

출처 및 근거

ORD 기록
ord-2f13c7f520be41dfb4bc8b7d3ebbc67d
출처 데이터셋
uspto-grants-2004_11
특허 번호
US06825170B2

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