4-(1H-Pyrazol-1-yl)benzaldehyde → (2E)-3-[3-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-2-propenal

HRID 2416484노트

반응식

HRID 2416484 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N:10]1[CH:14]=[N:13][CH:12]=[N:11]1)[CH:5]=O.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[F:1][C:2]1[CH:3]=[C:4](/[CH:5]=[CH:23]/[CH:24]=[O:25])[CH:7]=[CH:8][C:9]=1[N:10]1[CH:14]=[N:13][CH:12]=[N:11]1

참가 물질

3

반응물 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 162279523-fluoro-4-(1H-1,2,4-triazol-1-yl)benzaldehyde

생성물 1

HCID 22631053(2E)-3-[3-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-2-propenal

실험 절차

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 3-fluoro-4-(1H-1,2,4-triazol-1-yl)benzaldehyde (prepared as described in Reference Example 7) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 218 (M+H)+.

출처 및 근거

ORD 기록
ord-17ca1d1965df4b509f4126d401354ae7
출처 데이터셋
uspto-grants-2004_11
특허 번호
US06825170B2

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