3-(2-Pyridinyl)-5-isoxazolemethanol → 2-(5-Formyl-isoxazol-3-yl)-pyridine

HRID 2416554노트

반응식

HRID 2416554 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:11]=[C:10]([CH2:12][OH:13])[O:9][N:8]=1.N1C=CC=NC=1C1C=CC(C#CCO)=CC=1>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:11]=[C:10]([CH:12]=[O:13])[O:9][N:8]=1

참가 물질

3

반응물 2

HCID 6865423-(2-Pyridinyl)-5-isoxazolemethanolHCID 226311353-[4-(2-Pyrimidinyl)phenyl]-2-propyn-1-ol

생성물 1

HCID 226312282-(5-Formyl-isoxazol-3-yl)-pyridine

실험 절차

The title compound is prepared by a procedure analogous to Reference Example 300 by substituting 3-(2-pyridinyl)-5-isoxazolemethanol (prepared as described in J. Org. Chem. 2000, 65, 2225) for the 3-[4-(2-pyrimidinyl)phenyl]-2-propyn-1-ol of Reference Example 300. MS 175 (M+H)+.

출처 및 근거

ORD 기록
ord-00a04aa184834277b84eacda9316cab4
출처 데이터셋
uspto-grants-2004_11
특허 번호
US06825170B2

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