HCID 22632884, 화합물 → HCID 9820196, 화합물
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:17]3[C:12](=[CH:13][C:14]([F:23])=[C:15]([N:18]4[CH2:22][CH2:21][CH2:20][CH2:19]4)[CH:16]=3)[C:11](=[O:24])[N:10]([O:25]CC3C=CC=CC=3)[C:9]2=[O:33])=[CH:4][CH:3]=1>[Pd]>[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:17]3[C:12](=[CH:13][C:14]([F:23])=[C:15]([N:18]4[CH2:22][CH2:21][CH2:20][CH2:19]4)[CH:16]=3)[C:11](=[O:24])[N:10]([OH:25])[C:9]2=[O:33])=[CH:4][CH:3]=1참가 물질
3
실험 절차
Using the General Method 6A, the reaction of 10% Pd/C (0.027 g) with 1-(4-fluorophenyl)-6-fluoro-3-benzyloxy-7-pyrrolidin-1-yl-1H-quinazoline-2,4-dione (Example L-1, 0.08 g, 0.18 mmol) afforded 0.05 g of the title compound as a solid, mp 183-185° C.
출처 및 근거
- ORD 기록
- ord-1cdecc3ac6c64ef3ae4dbc531500007d
- 출처 데이터셋
- uspto-grants-2004_11
- 특허 번호
- US06825199B2
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