Boronic Acid → 2-Propyloxy-5,6,7,8-tetrahydro-5,5,8,8-tetra-methylnaphthylboronic acid

반응식

Br[C:2]1[C:3]([O:16][CH2:17][CH2:18][CH3:19])=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:13])([CH3:12])[C:10]=2[CH:11]=1.[BH:20]([OH:22])[OH:21]>>[CH2:17]([O:16][C:3]1[CH:2]=[CH:11][C:10]2[C:9]([CH3:13])([CH3:12])[CH2:8][CH2:7][C:6]([CH3:15])([CH3:14])[C:5]=2[C:4]=1[B:20]([OH:22])[OH:21])[CH2:18][CH3:19]

참가 물질

반응물 2

HCID 61668Boronic Acid

HCID 222527532-Bromo-3-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene

생성물 1

HCID 226346572-Propyloxy-5,6,7,8-tetrahydro-5,5,8,8-tetra-methylnaphthylboronic acid

실험 절차

In a similar manner to Example 3(a), by reaction of 8 g (24.6 mmol) of 3-bromo-2-propyloxy-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene, 5.7 g (80%) of the expected boronic acid are obtained, with a melting point of 138-9° C.

후처리

customare obtained, with a melting point of 138-9° C.

출처 및 근거

ORD 기록: ord-790107d14227438cb80bfc7d54f4a4c2
출처 데이터셋: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06825360B1

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