Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Chlorophenacyl bromide → 5-(4-Chlorophenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Chlorophenacyl bromide | HCID 68303 | — |
| 반응물 | O-Ethyl hydrazinecarbothioate | HCID 12567113 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 5-(4-Chlorophenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one | HCID 329473 | — |
반응 단계
A mixture of 2-bromo-1-(4-chloro-phenyl)-ethanone (90.71 mmoles) and hydrazine-carbothioic acid O-ethyl ester (90.71 mmoles) in acetonitrile (84 ml) is stirred at ambient temperature for 3 hours. The solid formed is filtered off, washed with acetonitrile and ethyl ether and then dried in vacuo to yield the title product, which is used directly in the next Step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08653073B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-ac965aab873d4f019cf92ec011495b64 |
| 출처 메모 | uspto-grants-2014_02 |